Endran Healer Differentiators

1. Same Ingredients, Reasonable Price

By utilizing the same salmon-derived PN ingredients as Rejuran, we can help reduce the financial burden of the procedure.

2. Not just simple injection, but a designed procedure

By precisely injecting the PN ingredients into the necessary layers and depths, tailored to the skin structure, we aim to increase satisfaction with the procedure.

3. Accuracy Verified by Papule Confirmation

Immediately after the procedure, we visually confirm the papule phenomenon (small bumps) that appears on the skin with the patient to ensure that the medication has reached the intended area.

4. From Consultation to Procedure, Directly Performed by the Director

After thoroughly diagnosing the patient's skin condition and past treatment history, we proceed with a 1:1 customized procedure.

5. Minimized Irritation, Designed for Recovery

After the procedure, we use a Jaungo modeling pack to comfortably soothe sensitive skin and aid in smooth recovery.

6. Papule Spacing Designed Differently for Each Area

We delicately adjust the PN injection interval considering the skin thickness, elasticity, and wrinkle direction of each facial area. For example, the cheeks and forehead are treated with wider spacing, while the areas around the eyes and mouth are treated more densely, ensuring a procedure tailored to the specific characteristics of each area.

Endran Healer, Why Should You Choose It?

1. An Option with Identical Ingredients

Since the patent for PN (Polynucleotide), the main ingredient of Rejuran, expired, various products utilizing similar salmon-derived PN have been launched on the market.

Endran Healer also contains the identical ingredients.

Therefore, it offers the advantage of receiving the procedure at a more reasonable cost.

If you are considering a PN treatment that maintains the desired results while reducing the burden of treatment costs,

Endran Healer can be an alternative.

2. More Important Than the Ingredients Is “How It's Injected”

Simply because PN ingredients are included does not mean everyone will achieve the same results.

The Endran Healer procedure goes beyond simple injection.

It involves precisely injecting, understanding each layer of the skin, and calculating the appropriate depth and necessary amount.

Considering each patient's individual skin thickness, degree of damage, and pore structure, the injection depth is meticulously adjusted to suit each skin layer.

This meticulous injection method can positively influence dermal remodeling and collagen regeneration.

3. Confirming Medication Injection Location Together with Papules

We have a procedure where both the medical staff and the patient visually confirm whether the PN medication has been accurately injected into the intended location.

The papule phenomenon that appears after the procedure is not merely an inconvenient side effect, but an indicator that the medication has successfully reached the target dermal layer.

Therefore, immediately after the procedure, we directly show and confirm the papule phenomenon with the patient.

We approach this with the belief that this short papule check process can significantly impact the procedure's results and patient satisfaction.

4. From Consultation to Procedure, the Director Handles 1:1

We prioritize direct communication with the medical staff over standardized explanations provided by a consultation manager.

The director personally and meticulously examines and assesses the patient's current skin condition, sensitivity, past treatment history, and even currently used products, from start to finish.

This detailed diagnostic process can help the PN ingredients work more effectively on the skin,

and can also contribute to preventing unnecessary inflammation or side effects that might occur.

5. Minimize Irritation, Speed Up Recovery

After the PN procedure, we conclude by including a Jaungo modeling pack as a standard step to help soothe and recover the skin.

5. 자극은 줄이고, 회복은 빠르게

PN 시술 후에는 피부 진정과 회복을 돕기 위해 자운고 모델링팩을 기본으로 포함하여 마무리해 드립니다.

We offer a complex herbal soothing treatment that rapidly calms skin redness, heat, and hypersensitivity.

This helps prevent the skin from overreacting and becoming sensitive.

Therefore, PN treatment can be considered even for thin or sensitive skin.

We also provide systematic aftercare to aid in a comfortable recovery after the procedure.

6. We meticulously design the embos spacing for each area.

During EndranHiller treatments, we carefully consider not only the injection points but also the spacing between each injection.

For instance, in areas with a thick and wide dermis, such as the cheeks or forehead,

the PN component spreads widely even with a single point injection, so desired results can be expected with 1-1.5cm spacing.

However, in areas where the skin is thin and wrinkles are delicately distributed, such as around the eyes or mouth,

injecting meticulously at 0.5cm intervals can help improve skin texture.

If the skin is generally thin with many sunken areas,

or if the skin's texture has become irregular due to laser treatments, we adjust the injection method to be more dense even for cheek or forehead areas.

Considering the skin's thickness, elasticity, wrinkle direction, and treatment goals,

we meticulously plan the location of the embos and injection intervals to suit each individual.

Even with the same volume (e.g., 2cc, 4cc) of treatment, results may vary due to this customized approach.

One of the characteristics of EndranHiller is individualized, customized treatment rather than a standardized method.

What expected effects can EndranHiller have?

1. It can promote collagen and elastin production, making the skin firmer.

The PN (polynucleotide) component extracted from salmon activates fibroblasts in the dermal layer of the skin,

helping to induce collagen and elastin production.

This can help improve skin thickness, reduce fine wrinkles, restore elasticity, and

also offer pore improvement benefits.

2. It can aid in the recovery of damaged skin barriers and enhance the skin's natural regenerative power.

PN promotes the secretion of growth factors such as TGF and FGF, contributing to epidermal cell regeneration and skin barrier strengthening.

Therefore, it can help improve inner skin dryness, reduce skin sensitivity, and enhance the skin's inherent recovery ability.

It can also contribute to the rapid calming and recovery of skin that has become sensitive after laser or peeling treatments.

3. Naturally improving skin condition

EndranHiller is not a procedure that directly adds volume like fillers or controls muscle movement like Botox.

By restoring the skin's inherent health, it is expected to refine skin texture, reduce inner skin tightness, and improve makeup adhesion.

If you desire improved skin health through natural changes, you can consult with a specialist to consider EndranHiller treatment.

Mechanism of Action of EndranHiller

1. It activates fibroblasts, contributing to the reconstruction of skin structure.

The main component of EndranHiller, PN (polynucleotide),

is a high-purity DNA fragment extracted from salmon, which, when injected into the dermal layer of the skin,

acts like a signal to damaged tissue, stimulating and activating fibroblasts.

Activated fibroblasts promote the production of skin components such as collagen, elastin, and hyaluronic acid,

which can help improve skin density and elasticity, and restore a healthy skin structure.

2. It promotes the secretion of growth factors, enhancing the skin's natural regenerative power.

Activated fibroblasts help secrete various growth factors important for skin regeneration and recovery.

TGF-β plays a role in promoting collagen synthesis.

FGF: Promotes skin regeneration and recovery

VEGF: Improves skin microcirculation

These growth factors create an environment that helps the skin regain its self-regenerative power.

Thus, they help the epidermal layer and skin barrier recover healthily.

This is expected to reduce sensitivity, improve inner dryness, and enhance overall skin recovery.

3. Improved Dermal Density for a Feeling of Fullness from Within

EndranHiller affects the dermis, a crucial part of the skin.

PN helps reconstruct the extracellular matrix (ECM) components like collagen, elastin, and hyaluronic acid that make up the dermis.

During this process, dermal tissue can be more densely filled with collagen, hyaluronic acid, and various proteins.

These changes can lead to increased inner skin elasticity, giving a firmer feel, and a smoother skin texture, allowing makeup to blend better.

4. Anti-inflammatory Function to Reduce Irritation and Aid Rapid Recovery

Beyond simple skin regeneration, PN can also help regulate micro-inflammatory responses within the skin.

Persistent redness

Skin that reacts sensitively to external stimuli

Sensitivity occurring after laser treatment

In such situations, it can help manage inflammatory responses while supporting the skin's recovery process.

Accordingly, EndranHiller can be considered a PN treatment that can be used with less burden, even on relatively sensitive skin.

EndranHiller Treatment Procedure

1. Skin Condition Assessment

Carefully examining factors such as individual skin thickness, elasticity, and sensitivity,

we create a customized plan for the depth and method of PN injection.

2. 1:1 Consultation with Medical Staff

Which areas need improvement and how the treatment scope will be set,

the medical staff will directly assess and design.

Considering each individual's skin characteristics, a customized treatment plan is established.

3. Application of Anesthetic Cream

PN is a procedure injected directly into the dermis.

For this, sufficient numbing time of about 20 to 30 minutes is allowed,

to help reduce any discomfort that may occur during the procedure.

4. EndranHiller Injection

PN components are carefully injected at the pre-planned depth and location.

The even distribution of the injected PN is immediately confirmed through the 'embossment' phenomenon (small bumps), and

the injection site is adjusted as needed to add precision.

5. Soothing Care with Jaun-go Modeling Pack

Immediately after the procedure, a Jaun-go modeling pack is used to

help alleviate minor irritation from the injection needle, redness, and heat sensation.

We manage the skin to regulate excessive reactions and ensure a comfortable overall recovery process.

EndranHiller Recommended Cycle and Duration

1. Initial Intensive Treatment (Total 3 Sessions)

We generally recommend 3 treatment sessions, spaced 1 month apart.

There is a clear reason for that.

The main ingredient, PN, needs to accumulate sufficiently in the dermal layer.

Only then can fibroblasts be actively stimulated.

This is because it allows the collagen remodeling process to occur stably.

2. Maintenance Treatment (Touch-up)

If you wish to maintain the effects of the treatment consistently,

we recommend a touch-up treatment approximately once every 6 months to a year.

While this may vary depending on an individual's skin condition or lifestyle,

generally, after completing 3 treatments, you can expect the effects to last for about 6 to 12 months.

3. How long do the treatment effects last?

Once the collagen remodeling process is complete,

the improvement in skin texture, elasticity, and density is expected to last for an average of 6 months or more.

However, the duration of maintenance may be somewhat shorter in the following situations:

If your skin is unusually thin or already highly damaged.

If you have lifestyle habits that are not good for skin health, such as smoking or excessive sun exposure.

4. When can I expect to experience the treatment effects?

Immediately after the treatment, temporary swelling or slight puffiness may occur.

Approximately 1 week after the treatment, you may notice improved makeup adherence and a beginning of refined skin texture.

By the 2nd to 3rd week, you can expect overall elasticity to improve, skin density to increase, and fine wrinkles to gradually diminish.

After completing all 3 treatment sessions, the positive changes in skin structure will become even more apparent, and you will experience an overall improvement in your skin condition.

How much pain is involved with Endran Hiller treatment?

Generally, it's a tolerable stinging sensation.

Since the PN component is directly injected into the dermal layer, it is not completely painless.

However, because the procedure is performed after a thorough numbing process, most patients receive the treatment well without significant discomfort.

Degree of pain felt by area

Areas around the cheeks, forehead, and mouth tend to have less sensation or almost none.

The areas around the eyes, bridge of the nose, and chin may experience a momentary stinging sensation.

In areas with enlarged pores, a somewhat heavy pressure might be felt.

Efforts to reduce pain

We allow sufficient time for the numbing cream to take effect to alleviate pain.

We inject the ingredients slowly and in small, divided amounts to minimize irritation.

We continuously check with the patient about their pain level during the procedure.

We enhance comfort with post-treatment care, including a soothing pack.

Who needs Endran Hiller treatment?

1. Those concerned about noticeable fine wrinkles

Especially when tiny fine wrinkles begin to appear densely around the eyes, sides of the cheeks, and mouth.

This treatment may be suitable for those who are hesitant about lifting or filler procedures and desire natural wrinkle improvement.

2. Those with increased skin sensitivity and easy redness

This includes cases where skin reactions occur just by changing existing cosmetics, or when frequent facial redness develops.

It can be considered when you wish to healthily restore a weakened skin barrier.

3. When makeup flakes or doesn't adhere well due to inner skin dryness

This treatment can be considered when your skin feels tight due to inner dryness, even if the surface is oily, and makeup tends to flake easily.

It may be suitable for those who are concerned about deep skin dehydration that is difficult to improve with general moisturizing care.

4. When the skin feels fatigued from frequent treatments

This can be considered when your skin has become sensitive or thin due to repetitive treatments like lasers or peelings.

It can be beneficial for those who wish to restore overall skin health and vitality.

5. When you want to improve skin density and texture

This can be considered when your skin elasticity has decreased, leading to an uneven facial contour and a sagging appearance.

It can be helpful for those who feel a weakened skin support in the cheekbone or cheek areas, or who are concerned about uneven skin texture.

Embossing Reaction After EndranHealer Treatment

Immediately after the EndranHealer treatment, small, raised bumps (embossing) may appear on the skin.

This embossing can be seen as a positive sign that the medication has been precisely delivered to the skin's dermal layer.

The phenomenon of the skin slightly rising is a normal reaction, and it can also indicate a high likelihood of good treatment results.

Most embossing naturally subsides within 1-2 days after the treatment.

However, if the skin is thin or dry, or in sensitive areas like around the eyes or mouth, it may last for 2-3 days, or even up to 4 days.

Rarely, it may persist for 5-7 days or more, but

if it's not accompanied by severe pain, heat, or excessive redness in the treated area, there is no need to worry significantly.

This can actually be seen as a positive outcome, as the medication is slowly absorbed by the skin and acts for a longer period.

Post-Treatment Precautions

• ✔ Slight unevenness, redness, and pain that may occur in the treated area typically last for about 2-3 days.
• ✔ Injection marks, bruising, or mild swelling may appear for up to 1-2 weeks after the treatment.
• ✔ For about 7 days after the treatment, it is advisable to avoid alcohol, smoking, saunas, swimming pools, and strenuous exercise, as these can irritate the skin.
• ✔ After the treatment, pay special attention to moisturizing care for skin soothing, and we recommend diligently applying sunscreen when going outdoors.